Israeli forces shot dead a 13-year-old boy during clashes south of al-Bireh in Ramallah district, medics said.
The child, identified as 13-year-old Ahmad Sharaka, was shot in the neck with a live round, medics said.
He was rushed to the Palestinian Medical Complex in Ramallah where doctors operated on him, before he succumbed to his wounds.
Sharaka’s death brings the total number of Palestinians killed to 24 since the beginning of October. He is also the third 13-year-old to be shot dead by Israeli forces in the same time period.
Another Palestinian was shot in his leg with a live round during the protest in the al-Balu area of southern Bireh, while another was injured by a rubber-coated steel bullet.
Two others reportedly suffered excessive tear gas inhalation at the protest.
Israeli bulldozers have reportedly removed large objects in the area, in order to remove cover for Palestinian protesters.
An Israeli army spokeswoman had no immediate comment.
In clashes across the occupied Palestinian territory, the Palestinian Red Crescent counted at least 55 Palestinians shot and injured with live fire, and 77 injured by rubber-coated steel bullets.